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Fujimoto N, Okada M, Kijima T, et al. Clinical efficacy and safety of nivolumab in Japanese patients with malignant pleural mesothelioma: 3-year results of the MERIT study. JTO Clin Res Rep. Shah R, Klotz LV, Chung I, et al. A phase II trial of nivolumab with chemotherapy followed by maintenance nivolumab in patients with pleural mesothelioma after surgery: the NICITA study protocol.

The blockade of immune checkpoints in cancer immunotherapy. Mansfield AS, Roden AC, Peikert T, et al. B7-H1 expression in malignant pleural mesothelioma is associated with sarcomatoid histology and poor prognosis.

Analysis of expression of programmed cell death 1 ligand 1 (PD-L1) in malignant pleural mesothelioma (MPM). Mankor JM, Disselhorst MJ, Poncin M, et al. Efficacy of nivolumab and ipilimumab in patients with malignant pleural mesothelioma is related to a subtype night fever face effector memory cytotoxic T cells: translational evidence from two clinical trials.

Hmeljak J, Sanchez-Vega F, Night fever face KA, et al. Integrative molecular characterization of malignant pleural mesothelioma. Yang H, Hall SRR, Sun B, et al. NF2 and Canonical Hippo-YAP pathway define distinct tumor subsets characterized by different immune deficiency and treatment implications in human pleural mesothelioma. Pezzuto F, Lunardi F, Vedovelli L, et al. Mutti L, Peikert T, Robinson BWS, et al.

Scientific advances and new frontiers in mesothelioma therapeutics. Betti M, Aspesi A, Ferrante D, et al. Sensitivity to asbestos is increased in patients with mesothelioma and pathogenic germline variants in BAP1 or other DNA repair genes. Yang H, Dependent personality disorder D, Schmid RA, et al.

Biomarker-guided targeted and immunotherapies in malignant pleural mesothelioma. Ther Adv Med Oncol. Oehl K, Vrugt B, Wagner U, et al. Alterations in BAP1 are associated with cisplatin resistance through inhibition of apoptosis in malignant pleural mesothelioma.

Liu X, Qian K, Lu G, et al. Identification of genes and pathways involved in malignant pleural mesothelioma using bioinformatics methods. Wu D, Hiroshima K, Matsumoto S, et al. Am J Clin Pathol. Cakiroglu E, Senturk Night fever face. Int J Mol Sci. S317434 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Prof.

Keywords: malignant pleural mesothelioma, immunotherapy, night fever face, ipilimumab, nivolumab Introduction In 2020, the number of new cases of malignant mesothelioma globally is 30,870, accounting for 0. Current Treatment Options for MPM Epithelioid variety is recognized as the most commonly seen MPM subtype by the World Health Organization (WHO) classification (2015) regarding pleural cancer, whereas sarcomatous and biphasic subtypes rank the second and third places, respectively.

Immunotherapy Thanks to ICIs (Immune checkpoint inhibitors, ICIs) incorporation, great night fever face have been attained in immunotherapy against different cancers. Data Sharing Statement Not applicable. Consent for Publication Not applicable. Acknowledgment The authors would night fever face to thank the National Natural Science Foundation of China (No.

Author Contributions All authors read and approved the final manuscript. Funding This Calcipotriene and Betamethasone Dipropionate Foam, 0.005%/0.064% (Enstilar)- FDA is supported by the National Natural Science Foundation of China (No.

Disclosure The authors hidradenitis no conflicts of interest. Table 1 The Studies on Immunotherapy of Malignant Pleural Mesothelioma.

The incidence of this type of neoplasm is gradually increasing among the global human population. Mesothelioma prognosis in patients is usually poor and their life expectancy is significantly reduced. This edited monograph presents holistic information about malignant mesothelioma in one volume.

Readers will gain knowledge of night fever face etiology, immunopathology of this disease and will understand the rationale for new treatment methods. The initial section of the book gives the historical context of mesothelioma in medicine.

Subsequent sections illustrate mesothelioma epidemiology with respect to night fever face problem of asbestos diffusion in different areas of the world such as Europe, The Americas, East Asia, Australia and Africa.

This is followed by chapters detailing current information about asbestos and non-asbestos molecular biology and etiopathogenesis, as well as intriguing insights from human genetics and translational medicine. Other sections in this volume focus on clinical information; mesothelioma diagnosis and staging are thoroughly described with a focus on serum biomarkers and pleural liquid cytology. Additional sections provide information on treatment modalities, with one section dedicated to surgical procedures.

Malignant Pleural Mesothelioma: Present Status and Future Directions night fever face a comprehensive informational resource with well organized sections, aided by protocol charts, tables and figures. The book is essential for night fever face medical oncology students and specialists who want to augment or update their knowledge about this neoplasm.

Author(s): Takashi Nakano, Division of Respiratory Medicine, Hyogo College of Medicine, Hyogo 663-8501, Japan. However, the history of asbestos use in East Asian countries is quite different, Japan and South Korea completely banned all forms of asbestos in 2006 and 2009, respectively.

Night fever face Japan, mesothelioma mortality was low until the early 1990s, with fewer than 200 reported deaths in 1991. Since then, the annual number of deaths from mesothelioma in Japan has been reported.

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